To investigate whether major chemokines are involved in the chemotaxis of microglia in this RP model, qRT-PCR for fractalkine/CX3CL1 and MCP-1/CCL2 was performed on the extracted retina of rd10 mice at 3 different time points during retinal degeneration (P17, 21, and 30). This evidence concerns the gene CX3CL1 and retinitis pigmentosa 1.