Since the functions of LINC01559 in GC were partially depended on miR-1343-3p-targeted PGK1 but completely mediated by activation of PI3K/AKT pathway, we sought to identify whether LINC01559 regulated another target gene to activate PI3K/AKT pathway independent of miR-1343-3p. This evidence concerns the gene AKT1 and gastric cancer.