KLK3 and pachyonychia congenita: Patients with significant PC at final pathology had higher preoperative PHI level (65.89 ± 33.26 vs 52.23 ± 25.11; p < 0.001), higher preoperative PSA level (10.32 ± 7.66 vs 8.19 ± 4.51; p = 0.002) and higher frequency positive DRE (33.1% vs 23.3%; p<0.05) in the comparison with the rest of patients.