Many previous studies14, 15, 16, 17, 18, 19, 20 have reported predictors of surgical difficulty during LC for AC, such as preoperative radiological findings (non‐visualized gallbladder on preoperative cholangiography, cystic duct length, gallbladder wall thickening, incarcerated stones in the gallbladder neck, fluid retention around the gallbladder), duration of raised CRP, white blood cell count, low albumin, high bilirubin, diabetes and male sex. Here, CRP is linked to diabetes mellitus.