In a human cell in vivo model, a bioactive fraction extracted from Psidium guajava (common guava) was shown to induce thrombopoietin production and increase platelet counts.29 Furthermore, in a murine model, an extract made from Carica papaya (common papaya) leaves was associated with a significant increase in platelet counts, compared with controls.30 In addition, both plants have been used to prevent thrombocytopenia in humans suffering from dengue fever as well.31 Here, THPO is linked to dengue disease.