THPO and Thrombocytopenia: In a human cell in vivo model, a bioactive fraction extracted from Psidium guajava (common guava) was shown to induce thrombopoietin production and increase platelet counts.29 Furthermore, in a murine model, an extract made from Carica papaya (common papaya) leaves was associated with a significant increase in platelet counts, compared with controls.30 In addition, both plants have been used to prevent thrombocytopenia in humans suffering from dengue fever as well.31