Older age, male gender, hypertension, hyperlipidemia, coronary artery disease, dyspnoea, haematocrit, brain natriuretic peptide (BNP) and N‐terminal prohormone BNP (NT‐pro‐BNP) were significantly different between those without and those with pulmonary hypertension (P < 0.05). This evidence concerns the gene NPPB and pulmonary hypertension.