Data were inconclusive for the remaining 8 variants, either because there were no homozygous carriers in UK Biobank (rs113403872 in PKLR, rs28928907 in MPL, rs33946267 in HBB, rs146220228 in WAS), or because the disease presented mild symptoms that are not easily detectable (rs35897051 and rs119468010 in MPO for myeloperoxidase deficiency). The gene discussed is MPL; the disease is myeloperoxidase deficiency.