Interestingly, the 17q23 amplicon where BRIP1 gene lies, encompasses known oncogenes RPS6KB1, TBX2 and PPM1D. 35In particular, TCGA showed a 3.2‐fold up‐regulation of BRIP1 in breast tumours compared with normal breast tissues.36 This evidence concerns the gene TBX2 and breast neoplasm.