Cockayne syndrome (CS) is an autosomal recessive genetic disorder caused predominantly by genetic mutations in the ERCC8 (CSA) or ERCC6 (CSB) gene50; it is characterized by early-onset neurodegeneration, growth failure, impaired nervous system development, abnormal photosensitivity, vision defects, and premature aging. This evidence concerns the gene ERCC6 and Cockayne syndrome.