Notably, the same SCAD-associated PHACTR1 locus and LRP1 locus alleles have been associated with cervical artery dissection17, which has been documented in 16.4% of individuals with FMD9, and migraine headache, which occurs in ~36% of individuals with SCAD7 and ~50% with FMD9. This evidence concerns the gene PHACTR1 and spontaneous coronary artery dissection.