PHACTR1 and spontaneous coronary artery dissection: A common variant on chromosome 6p24.1 in the PHACTR1 gene, rs9349379-A (minor allele frequency (MAF) ~0.4), has been associated with both FMD and SCAD (odds ratio (OR)FMD = 1.4, ORSCAD = 1.7)13,16.