With regard to percent changes for determining the timing of reimplantation, the AUC indicated that percent changes in the CRP (AUC = 0.464), the IL-6 (AUC = 0.534), the ESR (AUC = 0.527), and the fibrinogen (AUC = 0.586) were all poor markers when predicted persistent or recurrent infection. Here, ESR1 is linked to infection.