Although it was later announced that a phase III trial on Hepatocellular carcinoma did not improve overall survival, it was inferred that it is possible to perform integral tissue biomarker studies in patients with advanced hepatocellular carcinoma, pointing to the need for additional randomized studies to confirm whether MET inhibition can serve as a potential therapy for some patients with advanced hepatocellular carcinoma [48,49]. The gene discussed is MET; the disease is hepatocellular carcinoma.