Studies have shown that PROK2 might be involved in tumorigenic processes through regulating angiogenesis in glioblastomas [10] and in colorectal cancer [11], myeloid cell infiltration in pancreatic cancer [12], growth in hepatocellular carcinoma [13] and tumor progression in prostate cancer [14]. The gene discussed is PROK2; the disease is familial pancreatic carcinoma.