H2AX and ovarian cancer: Gene Set Enrichment Analysis (GSEA) demonstrated that gene sets (G2/M checkpoint: NES (normalized enrichment score) = 2.46, p < 0.001; E2F targets: NES = 2.30, p < 0.001 (Figure 2); DNA repair: NES = 2.15, p < 0.001; estrogen response: NES = 1.46, p = 0.048 (Figure 3); mitotic spindle: NES = 1.98, p < 0.001; mTORC1 signalling: NES = 1.6; p = 0.047 (Figure 4); and UV response: NES = 1.75, p = 0.004; were also enriched in the H2AX highly expressing ovarian cancers.