While there is an up-regulation of IL12Rβ2 mRNA in the placentomes of NR non-IUGR pregnancies, the present study did not investigate the amount of IL-12 in placentomes, or presence of other IL-12 receptors, and further work is needed to fully elucidate the implications of the increased IL12Rβ2 mRNA in the placentomes of NR non-IUGR pregnancies. This evidence concerns the gene IL12RB2 and fetal growth restriction.