AKT1 and type 2 diabetes mellitus: We recently found that post-ischemic AKT levels and phosphorylation are unaltered by IPC or T2D [44], leaving the possibility that phosphorylation patterns during the IPC stimulus and/or initial minutes of reperfusion might be modified with ALA; AKT phosphorylation at these times is linked to I-R outcomes and cardioprotection.