Similarly, in a model of global cerebral ischemia, which attempts to recreate ischemic brain injury due to cardiac arrest, HSP70 was mainly observed in the cornu amonis (CA) 3 and the dentate granules of the hippocampus that tend to survive the ischemic episode, whereas HSP70 was not induced in CA1 neurons [43]. This evidence concerns the gene HSPA1A and cardiac arrest.