Peak parasitemia was reduced from 16.9 ± 2.97% in the naïve mice to 4.9 ± 0.50% in mice receiving 9 million CD73+ B cell and to 0.72 ± 0.18% (p = 0.0079) in mice receiving 30 million CD73+ B cells. This evidence concerns the gene NT5E and parasitic infectious disease.