YAP1 and esophageal squamous cell carcinoma: In accordance with this, we discovered that YAP/TAZ not only interacts with TEAD1 but also with Smad2/3, indicating that P. gingivalis infection in ESCC may trigger the formation of a transcriptional complex, including YAP/TAZ, TEAD1, and Smads but not excluding others, synergistically modulating target genes.