TGFB1 and esophageal squamous cell carcinoma: Microbial dysbiosis in the upper digestive tract is linked to an increased risk of esophageal squamous cell carcinoma (ESCC); this study shows that invasion of the bacterium Porphyromonas gingivalis enhances the aggressive progression of ESCC via the TGFβ/Smad and TGFβ/YAP/TAZ pathways.