When assessing genes whose expression is significantly dysregulated, relative to control cells, in at least 9 MPS types/subtypes, following ten were found: IER3IP1, SAR1A, TMEM38B, PLCB4, SIN3B, ABHD5, SH3BP5, CAPG, PCOLCE2, and MN1. The gene discussed is TMEM38B; the disease is mucopolysaccharidosis.