Since several proteins like adaptor-related protein complex 2 (AP2B1) and immunoglobulin Lambda-like polypeptide 1(IGLL1), cell division cycle, and apoptosis regulator 1 (CCAR1) are altered in KC, there may be an altered proliferation and apoptosis-related program of these cells [30]. This evidence concerns the gene CCAR1 and keratoconus.