A study with 797 NSCLC patients using four different cohorts from Norway and Denmark [52] scored the percentages of CD8+ T cells compared to the total numbers of nucleated cells in the tumor stroma, and concluded that tumor stromal CD8+ TILs were an independent prognostic factor for DFS and OS in multivariate analysis (p < 0.001). This evidence concerns the gene CD8A and non-small cell lung carcinoma.