CDK2 and Parkinson disease: Since the identification of hNatB more than a decade ago, many studies have shown that it N-terminally acetylates important proteins such as actin, tropomyosin, CDK2, and α-Syn, and its function has connections to diseases such as hepatocellular carcinoma and Parkinson's disease (Starheim et al., 2008; Polevoda et al., 2003; Ametzazurra et al., 2008; Neri et al., 2017; Halliday et al., 2011; Spillantini et al., 1998).