Ten genes (WNT1, STAB1, MYT1, CDKN1A, CDKN1B, CDKN1C, KLF2, RUNX3, CDH1 and CNR1), which have been reported to be targeted by EZH2 in human tumours, were selected as candidate genes in BC. The gene discussed is KLF2; the disease is breast cancer.