Mutations in any of the two key proteins result in decreased plasma PPi level, what is the metabolic cause of two monogenic inherited calcification diseases, pseudoxanthoma elasticum and generalized arterial calcification in infancy; for a review, see Borst et al.18We have determined the transcription from genes Abcc6 and Enpp1 in the liver by qRT‐PCR before polytrauma and during the 4 days calcification and found no significant changes in the abundance of either mRNA (compared to the values obtained from livers before polytrauma treatment). The gene discussed is ENPP1; the disease is Pseudoxanthoma elasticum.