In another study with 114 patients with cancer and VTD and an incidence of relapse of 9%, the elevation of D-dimer and high-sensitivity C-reactive protein was predictors of relapse of the thromboembolic episode (D-dimer: HR 5.81; 95% CI 1.1–31.7; C-reactive protein: HR 9.82; 95% CI 19–52), and therefore, they may be useful to identify susceptible patients following the interruption of anticoagulation [54]. The gene discussed is CRP; the disease is cancer.