Dramatic difference was demonstrated between the low-density group of PD-L1+/CD8+ TILS, accounting for 73.7% (14/19) of poorly differentiated tumor cases, and the high-density group of PD-L1+/CD8+ TILS, taking up 10.5% (2/19) (P < 0.05) (Table 1). The gene discussed is CD8A; the disease is neoplasm.