To identify the mRNA expression of METTL3, METTL14, WTAP, ALKBH5, FTO, and YTHDF2 in the peripheral blood from RA patients and CON, we used qRT-PCR to assess these gene expressions in screening testing set consisting of 20 RA patients and 20 CON. This evidence concerns the gene YTHDF2 and rheumatoid arthritis.