SLKDT downregulated PPAR‐γ and C/EBP‐α mRNA expressions and upregulated PPAR‐α, CPT‐1, LPL, and CYP7A1 mRNA expressions to reduce adipocyte differentiation and fat accumulation, accelerate fat oxidation, and improve dyslipidemia, then inhibit the immune response and alleviate liver injury. This evidence concerns the gene CYP7A1 and metabolic syndrome.