As a result, ADAMTS1 (HR = 1.68, P < 0.001), ADAMTS2 (HR = 1.49, P < 0.001), ADAMTS3 (HR = 1.33, P < 0.001), ADAMTS5 (HR = 1.4, P < 0.002), ADAMTS6 (HR = 1.7, P < 0.001), ADAMTS7 (HR = 1.63, P < 0.001), ADAMTS8 (HR = 1.72, P < 0.001), ADAMTS9 (HR = 1.46, P < 0.001), ADAMTS12 (HR = 1.39, P < 0.001), ADAMTS14 (HR = 1.58, P < 0.001), ADAMTS15 (HR = 1.29, P < 0.001), ADAMTS18 (HR = 1.53, P < 0.001), and ADAMTS20 (HR = 1.67) were found to be closely related to OS in patients with GC (P < 0.001). The gene discussed is ADAMTS8; the disease is gastric cancer.