Moreover, the immunofluorescent staining (Fig. 7A) and qRT-PCR (Fig. 7B,C) results clearly showed increased production ofNLRP3, caspase-1 and IL-1β in corneal and conjunctival epithelia of DS mice, whereas their levels decreased by hADSC-Evs application. The gene discussed is IL1B; the disease is Dravet syndrome.