We did not find that eGFR confounded the previously reported associations between certain biomarkers and all-cause mortality, namely sTNF-R1, vWF, hFABP and NT-proBNP.19 Our findings are in keeping with earlier work demonstrating that inflammatory biomarkers such as IL-6, TNF-alpha, fibrinogen and albumin are associated with mortality independently of eGFR, even within the CKD population.18 43. This evidence concerns the gene TNF and chronic kidney disease.