Among the included methylation positions, individual methylation status of cg27456487 (MPO), cg05140293 (TTLL4), cg10152449 (CHST12), cg22291265 (SHANK1), cg18597188 (XRCC3), cg14533068 (SYNJ2), cg00081084 (TBCB) and cg20386404 (PTPN14) were significantly associated with AML survival, according to MethSurv online tools (https://biit.cs.ut.ee/methsurv/) (Supplementary Figure 5). Here, XRCC3 is linked to acute myeloid leukemia.