The tumor Ki-67 index of xenografted SNU-638 and A375 was decreased by 72% and 70%, respectively, in the OxPhos inhibition group with drug treatment, while in the SNU-638 and A375 drug-only treatment group, the Ki-67 index was decreased by about 20% and 15%, respectively, compared with that in untreated SNU-638 and A375 controls (Figure 6A). This evidence concerns the gene MKI67 and neoplasm.