Moreover, the Lactoferrin chimera (LFchimera), a heterodimeric peptide containing LFmpin f(265–284), and a part of LFcinB f(17–30), was successfully tested for its antimicrobial and antibiofilm activities against multispecies biofilms derived from subgingival plaque of periodontitis; LFchimera antimicrobial and antibiofilm activities were stronger than chlorhexidine and minocycline hydrochloride, usually used in oral care products [55]. This evidence concerns the gene LTF and periodontitis.