CISH and ovarian carcinoma: In vitro studies with herceptin—DGA-G4-CIS in HER-2 human ovarian cancer cell lines have shown that the complexes have outstanding characteristics, decreasing the half maximal inhibitory concentration and increasing neoplastic cell apoptosis, in correlation with the increased cell uptake compared to the dendrimeric conjugate DGA-G4-CIS and the CIS molecule alone.