PAH patients that carry the ABCC8 mutation are younger at diagnosis (14 years compared to 42 years for iPAH patients), but have a similar mPAP to iPAH patients (47.6 mmHg for ABCC8-mutated patients and 56.4 mmHg for iPAH patients) [79]. This evidence concerns the gene ABCC8 and pulmonary arterial hypertension.