In a retrospective study examining 360,250 people with T2D and 1,296,489 people without T2D, Subramanian et al. showed that T2D patients are at an increased risk of OSA, especially male patients with a high BMI with diabetic foot diseases, depression, hypertension, or CVD, as well as patients taking insulin [37]. The gene discussed is INS; the disease is depressive symptom measurement.