EPAS1 and multiple system atrophy: In addition, we evaluated molecular signs of hypoxia in the visual cortex, a brain region less affected in α‐synucleinopathies, in which we observed a numerical increase of HIF2α protein in MSA cases compared with controls, although not significantly (MSA vs C: P = 0.0892); see Table 1 and Supplementary Figure 2A,B.