Variable alterations in CD25, programmed cell death protein 1 (PD-1), C-C chemokine receptor type (CCR)6 and CD27 surface marker expression, as well as IFN-γ and IL-4 production, by peripheral blood MAIT cells from individuals with type 1 diabetes have also been reported in these studies [34, 35]. The gene discussed is PDCD1; the disease is type 1 diabetes mellitus.