Mean (SD) serum CRP was 46.98 ± 21.19 and 14.19 ± 8.21 mg/dL, in patients with LC-IPF and IPF only, while median serum CRP (IQR) was 33.20 ± 8.78 and 13.15 ± 7.59 MG/dL, in the two groups, p=0.002, respectively (Table 1). This evidence concerns the gene CRP and laryngotracheoesophageal cleft.