Severe COVID-19 cases were more likely to have higher blood level of ASAT(RR = 2.27, 95%CI: 1.76;2.94; P-value:< 0.001; n = 1538), CK(RR = 2.61, 95%CI: 1.35;5.05; P-value: 0.01; n = 1086), Creatininemia (RR =3.66, 95%CI: 1.53; 8.81; P-value: 0.02; n = 1084), LDH (RR =2.03, 95%CI: 1.42;2.90; P-value: 0.003; n = 1138) (Table 4). This evidence concerns the gene ABCB7 and COVID-19.