This review shows that patients with a severe form of COVID-19 have higher level of CK-MB,troponin I, D-dimer, prothrombin time, procalcitonin, interleukin-6, C-reactive protein, ALAT, ASAT, LDH, CK, total bilirubin, γ-GT, myoglobin, blood urea nitrogen, creatininemia and lower level of lymphocyte, thrombocytes, eosinophils, haemoglobin and albuminemia. This evidence concerns the gene CRP and COVID-19.