And the tanshinone IIA from Salvia miltiorrhiza promotes the survival of DA neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of PD by the suppression of microglial activation and reduced expression of NADPH oxidase and iNOS [20]. Here, FMO5 is linked to Parkinson disease.