Pan-cancer analysis of the correlation of GLI1 and GLI2 with 19,540 genes expressed in 30 tumor types revealed that GLI1 and GLI2 are mutually the most correlated genes (Fig. 1A), and that all HH and TGFB genes are in the top 20 percentiles of most correlated genes with GLI1 and GLI2, with one exception. Here, GLI2 is linked to neoplasm.