The lncRNA EMX2OS, which has been validated and identified to potentially induce proliferation and invasion, and promote sphere formation in ovarian cancer cells by regulating the miR-654-3p/AKT3/PD-L1 Axis28 Additionally, EMX2OS can be used as a biomarker in laryngeal cancer and papillary thyroid cancer29,30. Here, AKT3 is linked to laryngeal carcinoma.