Loss of FGF10-FGFR2B signaling in bronchial epithelial cells leads to impaired generation of both neo-basal cells and alveolar epithelial cells after bleomycin injury, which can cause IPF.324 Deletion of FGFRs (FGFR1, 2, and 3) in lung mesenchyme decreases pulmonary fibrosis development in response to bleomycin.325 FGF7 and FGF10 can improve the lung repair and increase the epithelial survival after injury through FGFR2b signaling in rodents. Here, FGFR1 is linked to pulmonary fibrosis.