The remaining 7 genes had no indications while with druggable evidence, including 3 genes (DAG1, IL27, STX4) predicted targeted for ulcerative colitis, 3 genes (IL27, IFNLR1, PPP5C) predicted targeted for ankylosing spondylitis, as well as 4 genes (IFNLR1, IL27, STAT2, IL18R1) predicted targeted for psoriasis (Figure 8 and Supplemental Table 16). Here, IL27 is linked to ankylosing spondylitis.