APLN and cardiac arrhythmia: More importantly, apelin decreased (P < 0.0001) the incidence arrhythmia inducibility (~44% to 0%) in association with decreased (P = 0.0039) arrhythmia duration (11.4 ± 4.0 s vs. 2.1 ± 0.8 s) compared with baseline (before apelin) (Figure 2, A–C).