HeLa cells and SH-SY5Y cells, a neuroblastoma line, showed a dense zone of vimentin staining next to the nucleus, which was absent in untreated cells, whether α-syn transfection – native or mutant forms of the protein associated with familial use PD – or MG132 treatment was used to generate the aggresomes (Fig. 1A–J). This evidence concerns the gene VIM and Parkinson disease.