PYCARD and myeloid sarcoma: For ASC, the authors found a cutoff point of 352.4 pg/mL (84% sensitivity, 90% specificity) and for caspase-1 the cutoff point was 1.30 pg/mL (89% sensitivity, 56% specificity), demonstrating the reliability of ASC and caspase-1 as biomarkers of MS [87].